D.D.S. Oral Biology and Pathology

Dr. Ghazizadeh's lab Faculty staff and students of OB&P

Department of Oral Biology and Pathology Faculty, Staff, and Graduate Students

The Department of Oral Biology and Pathology acts as a bridge between the traditional basic sciences and the clinical sciences related to oral health.  The department has made a major commitment to the development of new diagnostic technology and approaches for use in the preservation of the oral tissue and management of oral disease. Oral Biology and Pathology is one of the leading deparments in the University in technology development and translation to clinical practice. Withing the predoctoral dental curriculum the department offers approximately 400 hours of didactic instruction relevant to the understanding of biological and molecular processes involved in oral disease.  The sequencing of the units is designed to obtain maximum integration between concurrently offered basic science and clinical courses. During the first three years of the predoctoral program, the subject matter deals with:

  • the biology of embryological development of the face and oral cavity,
  • oral mineralized tissues,
  • dental supporting tissues,
  • oral microbiota,
  • salivary glands and their products,
  • oral and other mucous membranes,
  • the various sensory and oral motor systems of the mouth.

Oral pathology and oral medicine segments of the departments curriculum are offered in the latter two years of the predoctoral program.  Where possible, the didactic subject matter is coupled with actual patient examination and clinicopathological conferences.  Emphasis is placed on the inter-relationships of:

  • pathology,
  • clinical behavior,
  • prognosis,
  • therapeutic modality
  • and the biologic nature of the disease entity.

Division of Translational Oral Biology

Translational Oral Biology is an area of applied science that has been developed over a period of 35 years at the Stony Brook University School of Dental Medicine, where it exists as an important and unique component of the dental curriculum. It has been built on a growing foundation of oral and medically related biological science with a focus on clinical application and patient care.

The Translational Oral Biology curriculum for dental students is given in the third year and offers basic and practical experience in clinical laboratory methods and familiarizes students with investigative clinical procedures in the diagnosis and monitoring of the effectiveness of patient therapies. The curriculum is presently comprised of four sections. Section one deals with the nature and fundamentals of technology and knowledge transfer. Section two focuses on the fundamentals and specifics of newly developed and emerging diagnostic devices and techniques. Section three deals with the underlying basis and specifics of a range of new and emerging therapeutics and therapies. The fourth and last part deals with protocols to manage specific diseases where newly discovered and perfected diagnostic and therapeutic entities can be applied and integrated into clinical practice.

Dr. Lucille London and Dr. Raja Graduate Students at SRD Dr. Gu and Dr. Lee with Grad Student

HDO 501 Oral Biology I

Deals with the molecular structure, biochemistry, and physiology and developmental anatomy of the systems constituting the oral apparatus. Covers the embryological development of the face and oral cavity, the biology of the oral mucous membranes, and the biology of the dental mineralized tissues.
31 course hours, Dr. Ghazizadeh and faculty

HDO 601 Oral Biology II
A continuation of HDO 501 covering the biology of the dental supporting tissues, the biology of the salivary glands and their products, the microbiology of the oral cavity, and oral motor and sensory systems.
Prerequisites: HDO 501, HBM 531 or permission of the department
82 course hours, Dr. Walker and faculty

HDO 701 Oral Biology III
A continuation of HDO 601 emphasizing neurosensory aspects of the oral cavity such oral pain, mastication, swallowing, speech, taste, and smell.  This material is presented by  Drs. S. London, (Stony Brook School of Dental Medicine) and  A. Spielman (New York University College of Dentistry). .
Prerequisite: HDO 501 HDO 601
14 course hours, Dr. SD London and faculty

HDO 702 Oral Pathology
Covers the clinical and histopathologic manifestations of acquired, inherited and neoplastic diseases of the human oral cavity. Includes benign and malignant tumors of bone, odontogenic and non-odontogenic cysts and tumors, mucosal and salivary gland diseases, and oral manifestations of systemic diseases.
Prerequisites: HDO 501 HDO 601
78 course hours Dr. Odingo

HDO 703 Oral Pathology Conference I
Clinicopathologic case presentations and development of differential diagnosis skills.
Prerequisite: HDO 501 HDO 601 Corequisite: HDO 702
22 course hours Dr. Odingo

HDO 704 Translational Oral Biology
The clinical continuation of HDO 703 in which the principals of oral diagnostics are applied to patient care. Covers pharmacology in dental practice emphasizing clinical usage of antibiotics, sedatives, tranquilizers, and analgesics.  Drug interactions and side effects are discussed
Prerequisites: HDO 501 HDO 601
38 course hours, Dr.Jagwani and faculty

HDO 705 Oral Medicine
Introduces the principles of patient care related to stomatologic and dermatologic disease, neurologic abnormalities, hematologic disturbances, and the medically compromised patient.
Prerequisites: HDO 501 HDO 601
16 course hours, Dr. Odingo

HDO 706 Oral Facial Genetics
Focuses on the utilization, preparation and analysis of basic human genetics in clinical situations. Covers genetic disorders of the craniofacial complex and dentistry for the multiple handicapped patient.
Prerequisite: HD 507 or permission of instructor
24 course hours, Dr. Ghazizadeh

HDO 803 Oral Pathology Conference II
A continuation of HDO 702.
Prerequisites: HD 703
11 course hours, Dr. Odingo

Faculty Participation in interdisciplinary courses in the Undergraduate Dental Curriculum

HDI 601 Evidence Based Dentistry and Critical Thinking
Develop in dental students the basic skills needed to recognize quality of evidence in journals and to carry out evidence based analysis of literature, formulate hypothesis, and analyze data.
18 course hours,  Dr. Walker

HDI 602 Year II Research Selective 
This course is a lab-, clinic or IT-based practical course that begins in the summer of year 2 (as students transition from year 1 to year 2). Students will choose a laboratory or clinical mentor and spend ~ 2 months over the summer on a research project.  The students are required to present their project at the School of Dental Medicine Research. S London (OBP, Course Director)

HDI 704 Foundations in Dental Professional Development III
This course utilizes interactive lectures and small group activities to illustrate various ethical and professional dilemmas faced by dental practitioners.
10 course hours, Dr. S. London and faculty

HDI 804 Foundations in Dental Professional Development IV
The course utilizes small group activities to illustrate various ethical and professional dilemmas faced by dental practitioners.
13 hours, Dr. S. London

HDG 803 General Dentistry Seminar IV  This course is designed to evaluate the student's ability to access, critically appraise, demonstrate applicability, and communicate scientific and lay literature as it relates to the provision of evidence-based general dentistry.  24 hrs. DDS Year IV  S Walker (OBP, Course Director) & J Kilimitzoglou (General Dentistry).

HDI 806 Year IV Elective in Professionalism and Ethics
The seminar will address pressing ethical/professional challenges concerning the delivery of health care and profession of dentistry in the 21st century. It will be structured as an advanced introduction to professional dental ethics designed to afford the interested senior student an opportunity to meaningfully discuss and seek a reasoned position on an assortment of challenging ethical issues currently facing our profession. Selections from the current literature and relevant case studies will be utilized. 22 hrs. DDS Year IV. S London (OBP) & R. Iovino (OMFS, Course Director).

Selective Courses

(See HDI 821)
Research in Oral Biology and Pathology
Participation in a research project under faculty supervision; research paper required.
120 course hours, Dr. Walker and faculty